A Barcode-Free Combinatorial Screening Platform for Matrix Metalloproteinase Screening

作者:Rane Tushar D; Zec Helena C; Wang Tza Huei*
来源:Analytical Chemistry, 2015, 87(3): 1950-1956.
DOI:10.1021/ac504330x

摘要

Application of droplet microfluidics to combinatorial screening applications remains elusive because of the need for composition-identifying unique barcodes. Here we propose a barcode-free continuous flow droplet microfluidic platform to suit the requirements of combinatorial screening applications. We demonstrate robust and repeatable functioning of this platform with matrix metalloproteinase activity screening as a sample application.

  • 出版日期2015-2-3