A new hydroxytyrosol metabolite identified in human plasma: Hydroxytyrosol acetate sulphate

作者：Rubio Laura; Macia Alba; Valls Rosa M; Pedret Anna; Romero Maria Paz; Sola Rosa; Motilva Maria Jose^*

来源：Food Chemistry, 2012, 134(2): 1132-1136.

DOI：10.1016/j.foodchem.2012.02.192

• 3,4-DHPEA-EDA
• Bioavailability
• Hydroxytyrosol acetate sulphate
• Mass spectrometry
• Olive oil

We report progress in the study of olive oil phenolic metabolites in humans and identify a new hydroxytyrosol metabolite called hydroxytyrosol acetate sulphate, which was determined using tandem MS, after ingestion of 30 ml of olive oil with a high phenolic content (500 mg/kg oil), reaching a maximum concentration of 1.63 mu M. In order to understand and explain the generation of this metabolite, two different pathways are proposed.

• 出版日期2012-9-15