Application of magnetic nanoparticle for controlled tissue assembly and tissue engineering

作者：Lee Eunjee A; Yim Hyungu; Heo Jiseung; Kim Hwan; Jung Giyoung; Hwang Nathaniel S^*

来源：Archives of Pharmacal Research, 2014, 37(1): 120-128.

DOI：10.1007/s12272-013-0303-3

• Nanoparticles
• Tissue engineering
• Cell assembly
• Cell function

Magnetic nanoparticles have been subjected to extensive studies in the past few decades owing to their promising potentials in biomedical applications. The versatile intrinsic properties of magnetic nanoparticles enable their use in many biomedical applications. Recently, magnetic nanoparticles were utilized to control the cell's function. In addition, intracellular delivery of magnetic nanoparticles allowed cell's positioning by appropriate use of magnetic field and created cellular cluster. Furthermore, magnetic nanoparticles have been utilized to assemble more complex tissue structures than those that are achieved by conventional scaffold-based tissue engineering strategies. This review addresses recent work in the use magnetic nanoparticle for controlled tissue assembly and complex tissue formation.

• 出版日期2014-1