A Versatile Iridium(III) Metallacycle Catalyst for the Effective Hydrosilylation of Carbonyl and Carboxylic Acid Derivatives

作者：Corre Yann; Rysak Vincent; Trivelli Xavier; Agbossou Niedercorn Francine; Michon Christophe

来源：European Journal of Organic Chemistry, 2017, 2017(32): 4820-4826.

DOI：10.1002/ejoc.201700801

• Hydrosilylation
• Iridium
• Metallacycles
• Carbonyls
• Carboxylic acids

A versatile iridium(III) metallacycle catalysed rapidly and selectively the reduction of a large array of challenging esters and carboxylic acids as well as various ketones and aldehydes. The reactions proceeded in high yields at room temperature by hydrosilylation followed by desilylation. Although the reactions of various aldehydes and ketones resulted exclusively in alcohols, the hydrosilylation of esters led to alcohols or ethers, depending on the type of substrate. Regarding the carboxylic acids, again the nature of the reagent controlled the outcome of the hydrosilylation reaction, either alcohols or aldehydes being formed.

• 出版日期2017-9-1