Autoimmune Inner Ear Disease in Children

作者：Huang Natalie C; Sataloff Robert T^*

来源：Otology & Neurotology, 2011, 32(2): 213-216.

DOI：10.1097/MAO.0b013e318204ac01

• Autoimmune hearing loss
• Autoimmune inner ear disease
• Methotrexate
• Pediatric population
• Sensorineural hearing loss
• Steroids

Objective: To determine the response to treatment of pediatric patients diagnosed with autoimmune inner ear disease.
Patients: Seven children who presented with sensorineural hearing loss and were diagnosed with autoimmune inner ear disease.
Intervention: Diagnosis through blood testing. Treatment with steroids and/or cytotoxic medication.
Main Outcome Measures: Improvement in pure-tone average and speech discrimination scores on audiometric testing.
Results: Six of the 7 children (85.7%) improved with treatment, and the remaining patient had no measurable progression of disease.
Conclusion: Children with autoimmune inner ear disease seem to benefit from treatment with steroids and/or cytotoxic medication. Although such medications must be used with caution in the pediatric population, they should not be withheld simply because of young age.

• 出版日期2011-2