Audiovestibular findings in patients with Vogt-Koyanagi-Harada disease

作者：Noguchi Yoshihiro^*; Nishio Ayako; Takase Hiroshi; Miyanaga Masaru; Takahashi Hiroyuki; Mochizuki Manabu; Kitamura Ken

来源：Acta Oto-Laryngologica, 2014, 134(4): 339-344.

DOI：10.3109/00016489.2013.868604

• Hearing loss
• tinnitus
• vertigo
• dizziness
• long-term follow-up

Conclusion: The long-term follow-up study revealed a good audiovestibular prognosis in our patients with Vogt-Koyanagi-Harada disease (VKH) after adequate treatment. Objectives: To evaluate the audiovestibular findings and long-term prognosis of patients with VKH. Methods: A total of 82 ears in 41 patients (9 males and 32 females, aged 18-78 years) with VKH were examined in the audiovestibular study. Of the 41 patients, 16 patients with follow-up periods of more than 12 months (13158 months) were included in the long-term follow-up study. Audiovestibular examinations included pure-tone audiometry; positional, positioning, and spontaneous nystagmus tests; and a caloric test. Results: Among the 41 patients, 28 (68%) complained of auditory symptoms at the initial visit and 28 (68%) showed sensorineural hearing loss (SNHL). Of the 24 patients who underwent nystagmus tests, only 3 (13%) presented with vestibular symptoms whereas 11 (46%) had nystagmus. Among 32 ears in 16 patients enrolled in the long-term follow-up study, 19 ears showed SNHL at the initial visit. The SNHL returned to normal in 14 ears (74%) and remained minimal in severity in the other 5 ears (26%) at the last visit. None of the patients showed persistent or repetitive vestibular symptoms.

• 出版日期2014-4