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<jats:title>Abstract</jats:title><jats:sec><jats:title>Aim</jats:title><jats:p>To provide an update of the systematic review by Engebretson and Kocher J Clin Periodontol. 2013 Apr;40 Suppl 14:S153 on the effect of periodontal therapy on glycaemic control of people with diabetes.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>PubMed Literature search restricted to meta‐analyses published from 2013 to the present was conducted. The search resulted in seven meta‐analyses of <jats:styled-content style="fixed-case">RCT</jats:styled-content>s.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Reduction in <jats:bold>HbA1c</jats:bold> at 3–4 months was reported in all reviews for the treatment group ranging from <jats:bold>−0.27%</jats:bold> (95% <jats:styled-content style="fixed-case">CI</jats:styled-content>: −0.46, −0.07, <jats:italic>p</jats:italic> = .007) to −1.03% (95% CI: 0.36, −1.70, <jats:italic>p</jats:italic> = 0.003). At 6 months post‐treatment, an HbA1c reduction ranging from −0.02 (95% <jats:styled-content style="fixed-case">CI</jats:styled-content>: −0.20, −0.16, <jats:italic>p</jats:italic> = .84) to −1.18% (95% CI: 0.72%, 1.64%, <jats:italic>p</jats:italic> < 0.001) was reported.</jats:p></jats:sec><jats:sec><jats:title>Clinical relevance</jats:title><jats:p>The magnitude of the reduction in HbA1c, which is found to be associated with non‐surgical periodontal treatment in patients with diabetes, seems to have clinically significant effects on systemic health, and thus should have a place in the treatment of diabetic patients.</jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p>Periodontal treatment (<jats:styled-content style="fixed-case">SRP</jats:styled-content>) results in a statistically significant reduction in HbA1C levels at 3 months, with a lower reduction at 6 months.</jats:p></jats:sec>
- 出版日期2018-2
