科研之友
微信
新浪微博
Facebook
分享链接
摘要
A Cu-catalyzed Sommelet-Hauser dearomatization of dihydrophenanthridine and diazo compounds is reported for the synthesis of spiro-indolines. A spiro-structure with adjacent quaternary and tertiary carbon centers was constructed in one step as a single isomer. Increasing steric hindrance by introducing ortho-substituents dramatically improved substrate reactivity in this transformation.
- 出版日期2018-7-14
- 单位中国科学技术大学
