Clinical and laboratory trends in fetal lung maturity testing

作者：Grenache David G^*; Wilson Andrew R; Gross Gilad A; Gronowski Ann M

来源：Clinica Chimica Acta, 2010, 411(21-22): 1746-1749.

DOI：10.1016/j.cca.2010.07.025

• Fetal lung maturity
• Trends
• Survey
• Lamellar body count

Background The surfactant/albumin ratio is a popular fetal lung maturity (FLM) test that will be unavailable in the near future We conducted surveys of obstetricians and clinical laboratorians to assess FLM testing trends from the perspectives of both disciplines and to identify how both communities might adapt to the loss of the surfactant/albumin ratio.
Methods 2067 physicians were surveyed about their familiarity with and clinical utility of various ELM tests 6137 laboratorians were surveyed about their ELM test menu and volumes
Results. Twenty-five percent of physicians indicated a decrease in FLM test ordering and the frequency of FLM testing has decreased significantly (p=0 011) since 1998 The surfactant/albumin ratio is the most frequently offered FLM test and was the test of choice for 62% of physicians. Without the surfactant/albumin ratio. 68% of physicians would order the lecithin/sphingomyelin ratio and 44% would order the lamellar body count (LBC) which were offered by 18 and 13% of laboratories, respectively 16% of laboratories were planning to offer the LBC within 24 months.
Conclusions ELM testing is decreasing The loss of the surfactant/albumin ratio

• 出版日期2010-11-11