A Signaling-Induced Switch in Dicer Localization and Function

作者:Hu Fuqu; Lai Eric C; Okamura Katsutomo*
来源:Developmental Cell, 2014, 31(5): 523-524.
DOI:10.1016/j.devcel.2014.11.032

摘要

In this issue of Developmental Cell, Drake and colleagues (2014) report that Ras signaling results in Dicer phosphorylation, which induces its nuclear localization and modulates its function. This regulatory strategy, conserved in mammals, allows dynamic control of microRNA function required for Caenorhabditis elegans germline development and oogenesis.

  • 出版日期2014-12
  • 单位南阳理工学院