A novel N-O ligand for palladium-catalyzed Mizoroki-Heck reaction in neat water

作者：Wang Yufang; Yang Qichao; Yang Li; Shi Jianxin; Zhang Mingjie^*

来源：Tetrahedron Letters, 2013, 54(39): 5314-5317.

DOI：10.1016/j.tetlet.2013.07.097

• 1-(Morpholin-1-yl-pyridin-2-yl-methyl)-2-naphthol
• N-O ligand
• Palladium-catalyzed
• Water
• Reusable

1-(Morpholin-1-yl-pyridin-2-yl-methyl)-2-naphthol as a novel efficient N-O ligand has been developed for palladium-catalyzed Mizoroki-Heck reaction in neat water without the protection of an inert atmosphere. The reactions proceed smoothly and give the desired products in moderate to excellent yields. The catalyst system is reusable.

• 出版日期2013-9-25
• 单位南阳师范学院; 天津大学