科研之友
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摘要
Dimethyltin(IV) dichloride-catalyzed selective oxidation of 1,2-diols in water was achieved using dibromoisocyanuric acid (DBI) or Br-2 as oxidants. The catalyst activates the 1,2-diol moiety through the formation of stannylene acetal in addition to enhancing selectivity. Various cyclic and acyclic 1,2-diol substrates have been selectively oxidized affording alpha-hydroxyketones in good to excellent yields. This method is safe and simple in operation.
- 出版日期2013
