A zwitterionic Zn(II) benzothiazole nanohybrid conjugate as hydrolytic DNA cleavage agent

作者:Zehra Siffeen; Tabassum Sartaj; Al Lohedan Hamad A; Arjmand Farukh*
来源:Inorganic Chemistry Communications, 2018, 93: 69-72.
DOI:10.1016/j.inoche.2018.05.008

摘要

An organic-inorganic hybrid Zn(II) complex has been synthesized in a "zwitterionic" form which crystallizes in triclinic P1 space group possessing labile apical chlorine atoms. DNA interaction studies were performed to enunciate the binding strength. The hydrolytic cleavage potential of the complex was substantiated and the kinetic aspects of the mechanism followed are also discussed.

  • 出版日期2018-7