Microwave Assisted Synthesis of Novel Methylenebis{2-[(1-benzyl/cyclohexyl-1H-1,2,3-triazol-4-yl)methoxy]chalc ones} and Their Antibacterial Activity

作者：Ramesh S^*; Ashok D; Goud G Linga; Reddy V Prabhakar

来源：Russian Journal of General Chemistry, 2014, 84(8): 1608-1614.

DOI：10.1134/S1070363214080283

• antibacterial activity
• bis-1,2,3-triazoles
• chalcones
• click chemistry
• microwave irradiation

A series of novel methylenebis{2-[(1-benzyl/cyclohexyl-1H-1,2,3-triazol-4-yl)methoxy]chalcones} (IVa-IVn) have been synthesized by the Click reaction and Claisen-Schmidt condensation of 5,5'-methylenebis[2-(prop-2-yn-1-yloxy)benzaldehyde] under microwave irradiation with high yields. All products have been characterized by spectral data including FT-IR, H-1, and C-13 NMR, mass spectrometry, and tested for their antibacterial activity.

• 出版日期2014-8