A New Dibenzocyclooctadiene Lignan from the Fruits of Schisandra lancifolia and Its Cytotoxicity

作者:Yang Hai Ying; Shen Guang Jian; Li Yin Ke; Wu Xian Xue; Du Gang; Hu Qiu Fen; Gao Xue Mei*
来源:Asian Journal of Chemistry, 2014, 26(11): 3152-3154.
DOI:10.14233/ajchem.2014.15854

摘要

A new dibenzocyclooctadiene lignan, lanciphenol B (1) was isolated from the fruits of Schisandra lancifolia. The structure of 1 was elucidated by spectroscopic methods including extensive 1 D-and 2 D-NMR techniques. Compound 1 was evaluated for its cytotoxicity, and showed cytotoxicity against NB4 and MCF7 cell with IC50 values of 7.8 and 8.9 mu M, respectively.

全文