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摘要
A novel dimeric flavonol glycoside, Cynanflavoside A (1), together with six analogues, kaempferol-3-O-alpha-L-rhamnopyranosyl-(1 -> 2)-beta-D-glucopyranoside (2), quercetin-3-O-alpha-L-rhamnopyranosyl-(1 -> 2)-beta-D-glucopyranoside (3), kaempferol-3-O-alpha-L-rhamnopyranosyl-(1 -> 2)-beta-D-xylopyranoside (4), quercetin-3-O-alpha-L-rhamnopyranosyl-(1 -> 2)-beta-D-xylopyranoside (5), kaempferol-3-O-beta-D-glucopyranosyl-7-O-alpha-L-rhamnopyranoside (6), and quercetin-3-O-galactoside (7) were isolated from the n-butyl alcohol extract of Cynanchum acutum subsp. sibiricum. Their structures were determined spectroscopically and compared with previously reported spectral data. All compounds were evaluated for their anti-complementary activity in vitro, and only compound 5 exhibited anti-complement effects with CH50 value of 0.33 mM. @@@ [GRAPHICS] @@@ .
