Allergic rhinitis and allergy are risk factors for otitis media with effusion: A meta-analysis

作者：Cheng, X.; Sheng, H.; Ma, R.; Gao, Z.; Han, Z.; Chi, F.^*; Cong, N.; Wang, J.; Liu, X.; Luo, X.; Yu, J.; Ra, Y.

来源：Allergologia et Immunopathologia, 2017, 45(1): 25-32.

DOI：10.1016/j.aller.2016.03.004

• allergic rhinitis
• Allergy
• Meta-analysis
• Otitis media with effusion

Objective/Hypothesis We systematically reviewed the associations between allergic rhinitis or allergy and otitis media with effusion, by reference to published data.
Study design: A meta-analysis of case-controlled studies.
Data source: Five databases (Pubmed, Highwire, Medline, Wanfang, and China National Knowledge Infrastructure) were searched for relevant studies in the English language published prior to November 12, 2015.
Studies chosen: Studies with clearly defined experimental and control groups, in which the experimental groups had otitis media with effusion together with allergic rhinitis or allergy, were selected.
Methods: We performed a meta-analysis on data from the identified cross-sectional and case-controlled studies using fixed- or random-effects models (depending on heterogeneity). We used Reviewer Manager 5.3 software to this end.
Results:Seven studies met the inclusion criteria. The prevalence of allergic rhinitis in patients with otitis media with effusion and the control groups differed significantly in three studies (P < 0.00001), as did the prevalence of allergy (in six studies; P = 0.003).
Conclusion: Allergic rhinitis and allergy appear to be risk factors for otitis media with effusion.

• 出版日期2017-2
• 单位复旦大学