A mild and efficient four component one-pot synthesis of 2,4,5-triphenyl-(1H-1-imidazolyl)isoxazoles catalyzed by ceric ammonium nitrate

作者：Rajanarendar E^*; Murthy K Rama; Reddy M Nagi

来源：Indian Journal of Chemistry - Section B: Organic and Medicinal Chemistry , 2011, 50(7): 926-930.

• Ceric ammonium nitrate
• triphenyl imidazolyl isoxazoles
• one-pot synthesis

Ceric ammonium nitrate (CAN) acts as an efficient catalyst for the synthesis of 2,4,5-tripheny1-1H-1-imidazolyl isoxazoles in a four component one-pot condensation of benzil or benzoin, aromatic aldehyde, isoxazole amine and ammonium acetate. This one-pot procedure is very simple, affording excellent yields in shorter reaction time at ambient temperature. Isoxazole amines are employed as one of the synthon in this multi-component condensation for the first time.

• 出版日期2011-7