NICKEL-CATALYZED BOLYLATION OF ARYL HALIDES WITH 4,4,6-TRIMETHYL-1,3,2-DIOXABORINANE

作者：Murata Miki^*; Sogabe Yosuke; Namikoshi Takeshi; Watanabe Shinji

来源：Heterocycles, 2012, 86(1): 133-138.

DOI：10.3987/COM-12-S(N)28

• Nickel Catalyst
• Borylation
• Hydroborane
• Aryl Halide
• Cross-Coupling

The nickel-catalyzed borylation of aryl iodides and bromides with 4,4,6-trimethyl-1,3,2-dioxaborinane was achieved. The mild reaction conditions employed allowed for the inclusion of common functional groups in aryl halides to be tolerated. A DFT study on the catalytic cycle shows that C-B bond formation occurs through sigma-bond metathesis between dialkoxyborane and arylnickel(II) halide intermediates.

• 出版日期2012-12-31