Hidden symmetries in the primary sequences of beta-barrel family

作者:Ji Xiaofeng; Chen Hanlin; Xiao Yi*
来源:Computational Biology and Chemistry, 2007, 31(1): 61-63.
DOI:10.1016/j.compbiolchem.2007.01.002

摘要

In this paper, we analyze the symmetries of beta-barrel proteins at both structure and sequence levels by using a modified recurrent quantification analysis. It shows that the structures and sequences have the same two-fold symmetry, although the later diverged considerably. This result may be helpful to understand the mechanism of protein evolution.