Autonomic mediation of the interdependence between variability signals of heart rate and blood pressure in the lizard Gallotia galloti

作者：De Vera Luis^*; Rial Ruben V; Pereda Ernesto; Gonzalez Julian J

来源：Canadian Journal of Zoology, 2012, 90(7): 839-848.

DOI：10.1139/Z2012-052

• autonomic nervous system
• cardiovascular variability
• Gallotia gallon
• Gallot%26apos
• s lizard
• nonlinear methods
• spectral analysis
• synchronization

Autonomic nervous system (ANS) involvement in the mediation of the synchronization between beat-to-beat RR interval variability (RRIV) and systolic blood pressure variability (SBPV) signals of the lizard Gallotia galloti (Oudart, 1839) was investigated through linear and nonlinear time series analysis methods in a pharmacological blockade context. The ANS blockers used were atropine, prazosin, and propranolol. The interdependence between the signals was quantified by means of the magnitude-squared coherence (MSC), which measures amplitude and phase linear synchronization; the phase lag index (PLI), which evaluates the phase synchronization; and the index L, which quantifies the generalized linear and nonlinear synchronization. Atropine decreased the PLI in the low-frequency (LF: 0.01-0.05 Hz) range; prazosin decreased the MSC in the medium-frequency (MF: 0.06-0.15 Hz) range; and propranolol did not alter any of the interdependence measures. It is suggested that (i) the cholinoceptor activity mediates the phase cardiovascular synchronization in the LF range; (ii) the alpha(1)-adrenoceptor activity mediates the amplitude and phase linear cardiovascular synchronization in the MF range; and (iii) the beta-adrenoceptor activity plays no role in mediating any dynamics of cardiovascular synchronization in the studied frequency range. When comparing these results with those in mammals, a lesser overall autonomic involvement in the mediation of the studied cardiovascular interdependences is seen in reptiles.

• 出版日期2012-7