Asymmetric alpha-Sulfonyl-and alpha-Phosphoryl-Oxylation of Ketones by a Chiral Hypervalent Iodine(III)

作者：Levitre Guillaume; Dumoulin Audrey; Retailleau Pascal; Panossian Armen; Leroux Frederic R; Masson Geraldine^*

来源：Journal of Organic Chemistry, 2017, 82(22): 11877-11883.

DOI：10.1021/acs.joc.7b01597

An enantioselective direct oxygenation of propiophenone derivatives mediated by a catalytic or stoichiometric amount of new chiral non-C2-symmetric iodoarenes(III) is reported. The reaction gives an easy entry to optically active alpha-sulfonyl- and alpha-phosphoryl oxyketones in respectable yields and enantioselectivities.

• 出版日期2017-11-17