Ambient Analysis of Saturated Hydrocarbons Using Discharge-Induced Oxidation in Desorption Electrospray Ionization

作者：Wu Chunping; Qian Kuangnan; Nefliu Marcela; Cooks R Graham^*

来源：Journal of the American Society for Mass Spectrometry, 2010, 21(2): 261-267.

DOI：10.1016/j.jasms.2009.10.006

Saturated nonfunctionalized hydrocarbons can be oxidized in situ by initiating an electrical discharge during desorption electrospray ionization (DESI) to generate the corresponding alchohols and ketones. This form of reactive DESI experiment can be utilized as an in situ derivatization method for rapid and direct analysis of alkalies at atmospheric pressure without sample preparation. Betaine aldehyde was incorporated into the DEST spray Solution to improve the sensitivity of detecting the long-chain alcohol oxidation products. The limit of detection for alkalies (C(15)H(32) to C(30)H(62)) from pure samples is similar to 20 ng. Multiple oxidations and dehydrogenations occurred during the DEST discharge, but no hydrocarbon fragmentation was observed, even for highly branched squalane. Using exact mass measurements, the technique was successfully implemented for analysis of petroleum distillates containing saturated hydrocarbons.

• 出版日期2010-2