Are home ventilators able to guarantee a minimal tidal volume?

作者：Fauroux Brigitte^*; Leroux Karl; Pepin Jean Louis; Lofaso Frederic; Louis Bruno

来源：Intensive Care Medicine, 2010, 36(6): 1008-1014.

DOI：10.1007/s00134-010-1785-9

• Non-invasive ventilation
• Tidal volume
• Airway resistance
• Compliance
• Air leak
• Patient-ventilator dyssynchrony

The aim of the study was to evaluate the ability of home ventilators to maintain a minimal tidal volume during different conditions associated with alveolar hypoventilation.
Bench evaluation coupled with an in vivo study on two healthy subjects.
Tertiary university hospital and research unit.
Six ventilators having a "volume guarantee" module (Synchrony II, Philips Respironics; Vivo 40, Breas; Legendair, Airox; Elisee 150, Philips Respironics; Ventimotion, Weinmann; and VS III, Resmed) were tested on a lung bench in a baseline condition and in three conditions associated with alveolar hypoventilation: increase in airway resistance, decrease in lung compliance, and non-intentional leaks. An in vivo study completed the bench study for the non-intentional leak condition.
The six ventilators were able to maintain a minimal tidal volume during an increase in airway resistance and a decrease in lung compliance. The maintenance of a minimal tidal volume during a non-intentional leak was more difficult and was associated with large variations in tidal volume, a default of pressure support delivery for some devices, and patient-ventilator dyssynchrony, both during the bench and the in vivo study.
The six home ventilators tested in the study were able to maintain a minimal tidal volume during an increase in airway resistance and a decrease in lung compliance, but not during a non-intentional leak.

• 出版日期2010-6