BODIPY-Au(I): A Photosensitizer for Singlet Oxygen Generation and Photodynamic Therapy

作者：Ucuncu Muhammed; Karakus Erman; Demirci Eylem Kurulgan; Sayar Melike; Dartar Suay; Emrullahoglu Mustafa^*

来源：Organic Letters, 2017, 19(10): 2522-2525.

DOI：10.1021/acs.orglett.7b00791

Upon complexation with Au(I), a photoinactive BODIPY derivative was transformed into a highly photoactive triplet sensitizer. Along with high efficiency in singlet oxygen generation (Phi(Delta) = 0.84), the new BODIPY Au(I) skeleton showed excellent photocytotoxic activity against cancer cell lines (EC50 = 2.5 nM).

• 出版日期2017-5-19