Associations of cardiorespiratory fitness, physical activity, and adiposity with arterial stiffness in children

作者：Veijalainen A^*; Tompuri T; Haapala E A; Viitasalo A; Lintu N; Vaisto J; Laitinen T; Lindi V; Lakka T A

来源：Scandinavian Journal of Medicine & Science in Sports, 2016, 26(8): 943-950.

DOI：10.1111/sms.12523

• Endothelial function
• physical fitness
• exercise
• adiposity
• atherosclerosis
• arterial stiffness

Associations of cardiorespiratory fitness (CRF), physical activity (PA), sedentary behavior, and body fat percentage (BF%) with arterial stiffness and dilation capacity were investigated in 160 prepubertal children (83 girls) 6-8 years of age. We assessed CRF (watts/lean mass) by maximal cycle ergometer exercise test, total PA, structured exercise, unstructured PA, commuting to and from school, recess PA and total and screen-based sedentary behavior by questionnaire, BF% using dual-energy X-ray absorptiometry, and arterial stiffness and dilation capacity using pulse contour analysis. Data were adjusted for sex and age. Poorer CRF (standardized regression coefficient =-0.297, P<0.001), lower unstructured PA (=-0.162, P=0.042), and higher BF% (=0.176, P=0.044) were related to higher arterial stiffness. When CRF, unstructured PA, and BF% were in the same model, only CRF was associated with arterial stiffness (=-0.246, P=0.006). Poorer CRF was also related to lower arterial dilation capacity (=0.316, P<0.001). Children with low CRF (<median) and high BF% (median; P=0.002), low CRF and low unstructured PA (<median; P=0.006) or children with low unstructured PA and high BF% (P=0.005) had higher arterial stiffness than children in the opposite halves of these variables. Poor CRF was independently associated with increased arterial stiffness and impaired arterial dilation capacity among children.

• 出版日期2016-8