Novel nickel-catalyzed coupling reaction of allyl ethers with chlorosilanes, alkyl tosylates, or alkyl halides promoted hy vinyl-Grignard reagent leading to allylsilanes or alkenes

作者：Terao J^*; Watabe H; Watanabe H; Kambe N

来源：Advanced Synthesis & Catalysis, 2004, 346(13-15): 1674-1678.

DOI：10.1002/adsc.200404192

• alkyl tosylates
• allyl ethers
• carbon-carbon bond formation
• carbon-silicon bond formation
• chlorosilanes
• Grignard reagents
• nickel

A new method for a carbon-silicon or carbon-carbon bond forming reaction between allyl ethers and chlorosilanes, alkyl tosylates, or alkyl halides giving rise to allylsilanes or alkenes has been developed. This reaction proceeds efficiently at ambient temperature by the combined use of nickel catalysts and a vinyl-Grignard reagent. A possible reaction pathway involving the formation of allyl-Grignard reagents via transmetallation of pi-allyl-nickel complexes with the vinyl-Grignard reagent and subsequent trapping of the thus formed allyl-Grignard reagents with electrophiles is proposed.

• 出版日期2004-12