科研之友
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摘要
Hyperleukocytosis is a leukemia-related condition characterized by an extremely high white blood cell count. Symptomatic leukostasis represents a medical emergency which needs to be promptly recognized and adequately managed in order to prevent early mortality and severe morbidity. Any organ may be affected, but intracranial hemorrhage and respiratory failure are the most frequent life-threatening complications of leukostasis. Since there are not clear guidelines on hyperleukocytosis treatment, this condition remains a challenge for physicians. Our review focuses on clinical manifestations of hyperleukocytosis and possible therapeutic approaches in order to provide a practical guide for early diagnosis and proper management of hyperleukocitic leukemia. Eur. J. Oncol., 16 (4), 221-231, 2011
- 出版日期2011
