BURSTING INDUCED BY EXCITATORY SYNAPTIC COUPLING IN THE PRE-BOTZINGER COMPLEX

作者：Duan Lixia^*; Zhai Dehong; Tang Xuhui

来源：International Journal of Bifurcation and Chaos, 2012, 22(5): 1250114.

DOI：10.1142/S0218127412501143

• Bursting
• bifurcation
• synaptic coupling
• fast-slow decomposition
• pre-Botzinger complex

In this paper, we study and classify the bursting in a two-cell network of excitatory neuron within the pre-Botzinger complex of the mammalian brain stem. We investigate the effects of parameters g(Na) and g(K) on the bursting generation and pattern transitions in the two-cell model network with synaptic coupling by the fast-slow decomposition and bifurcation analysis approach. Comparing the firing patterns of the uncoupled and coupled cells, we found that the bursting patterns are the same both for a single and two-cell model network with the parameter g(Na) changed, while they are different with the parameter g(K) changed. Our results are instructive for further understanding the dependence of the complex firing activities of the network on the firing activities of the single cell in the network.

• 出版日期2012-5
• 单位北方工业大学