A Coumarin-based Fluorescent Sensor for Selective Detection of Copper (II)

作者:Wang, Jian-Hong*; Guo, Xin-Ling; Hou, Xu-Feng; Zhao, Hui-Jun; Luo, Zhao-Yang; Zhao, Jin
来源:BULLETIN OF THE KOREAN CHEMICAL SOCIETY, 2014, 35(8): 2400-2402.
DOI:10.5012/bkcs.2014.35.8.2400

摘要

Cu (II) detection is of great importance owing to its significant function in various biological processes. In this report, we developed a novel coumarin-based chemosensor bearing the salicylaldimine unit (2) for Cu2+ selective detection. The results from fluorescence spectra demonstrated that the sensor could selectively recognize Cu2+ over other metal cations and the detection limit is as low as 0.2 mu M. Moreover, the confocal fluorescence imaging in HepG2 cells illustrated its potential for biological applications.