Analysis of curative effect of fluoxetine and escitalopram in the depression treatment based on clinical observation

作者：Zhang Xiaoling; Han Yunping; Lian Yingdong^*

来源：Pakistan Journal of Pharmaceutical Sciences, 2018, 31(3): 1115-1118.

• Fluoxetine
• escitalopram
• clinical efficacy
• interleukin
• mental anxiety
• drug reaction

Depression is a common affective disorder or mood disorder, which seriously affects people's physical and mental health and the quality of life. This study compared efficacy of escitalopram and fluoxetine on depression patients, and analyzed the inflammatory factors, serum homocysteine (Hcy) levels and the effects of adverse reactions, so as to provide reference for the clinical. The results showed that the total effective rate of the observation group (90.7%) was higher than that of the control group (80%), but the difference was not statistically significant (p>0.05). The total score of Hamilton Depressive Scale (HAMD) and mood in the observation group was significantly lower than that in the control group after treatment. To sum up, escitalopram and fluoxetine are effective in the treatment of depressive patients, but escitalopram can significantly improve the patient's micro inflammation and depressive symptoms

• 出版日期2018-5
• 单位山东医学高等专科学校