Mitochondrial Genomic Dysfunction Causes Dephosphorylation of Sch9 in the Yeast Saccharomyces cerevisiae

作者:Kawai Shigeyuki*; Urban Joerg; Piccolis Manuele; Panchaud Nicolas; De Virgilio Claudio; Loewith Robbie
来源:Eukaryotic Cell, 2011, 10(10): 1367-1369.
DOI:10.1128/EC.05157-11

摘要

TORC1-dependent phosphorylation of Saccharomyces cerevisiae Sch9 was dramatically reduced upon exposure to a protonophore or in respiration- incompetent rho(0) cells but not in respiration- incompetent pet mutants, providing important insight into the molecular mechanisms governing interorganellar signaling in general and retrograde signaling in particular.

  • 出版日期2011-10