Are older Western Australians exposed to potentially inappropriate medications according to the Beers Criteria? A 13-year prevalence study

作者：Price Sylvie D^*; Holman C D' Arcy J; Sanfilippo Frank M; Emery Jon D

来源：Australasian Journal on Ageing, 2014, 33(3): E39-E48.

DOI：10.1111/ajag.12136

• aged
• inappropriate prescribing
• prevalence
• risk factor
• Western Australia

Aim: To examine time trends and factors associated with exposure to potentially inappropriate medications (PIMs) by the Beers Criteria. %26lt;br%26gt;Methods: PIM consumption days accumulated from the pharmaceutical claims of 251 305 Western Australians aged %26gt;= 65 years (1993-2005) and person follow-up times produced counts/rates. Logistic/Poisson regression generated odds/rate ratios. %26lt;br%26gt;Results: A total of 187 616 participants (74.7%) took %26gt;= 1 PIM (1993-2005), the cohort consuming 109 415 PIM daily doses/1000 person-years. Annual exposure decreased from 45-47% to 40%, and annual consumption rate declined from 117 836 to 90 364 daily doses/1000 person-years. Temazepam had the highest exposures (%26gt;17 000 daily doses/1000 person-years). Number of medications taken (OR 35.03; 95% CI 34.37-35.71 for %26gt;= 10 vs. 0-2 drugs), annual drug intake (2.08; 2.04-2.12 for highest vs. lowest quartile), and high-level residential aged care (1.96; 1.91-2.01) were most predictive of PIM exposure. %26lt;br%26gt;Conclusions: PIM exposure remains high in older Western Australians. Our findings identify patients most at risk and medications to consider on Australia-specific PIM lists.

• 出版日期2014-9