An unusual spirocyclic isopimarane diterpenoid and other isopimarane diterpenoids from fruiting bodies of Xylaria polymorpha

作者：Shiono Yoshihito^*; Matsui Norika; Imaizumi Takayuki; Koseki Takuya; Murayama Tetsuya; Kwon Eunsang; Abe Tomomi; Kimura Ken ichi

来源：Phytochemistry Letters, 2013, 6(3): 439-443.

DOI：10.1016/j.phytol.2013.05.008

• Xylaria polymorpha
• Fruiting body
• Ca2+ signaling

Two new isopimarane-type diterpenes, spiropolin A (1) and myrocin E (3), were isolated from Xylaria polymorpha together with the known compound, myrocin D (2), in the course of a screening of the fruiting bodies of X. polymorpha. Their structures were determined on the basis of spectroscopic analysis, chemical conversion and X-ray analysis. Spiropolin A (1) restored the growth inhibition caused by the hyperactivated Ca2+-signaling in mutant yeast.

• 出版日期2013-8