Ultrasound Accelerated Thrombolysis May Be an Effective and Safe Treatment Modality for Intermediate Risk/Submassive Pulmonary Embolism

作者：Ozmen Caglar^*; Deniz Ali; Akilli Rabia Eker; Deveci Onur Sinan; Cagliyan Caglar Emre; Aktas Hahl; Celik Aziz Inan; Akpinar Ayca Acikalin; Disel Nezihat Rana; Balli Huseyin Tugsan; Hanta Ismail; Demir Mesut; Usal Ayhan; Kanadasi Mehmet

来源：International Heart Journal, 2016, 57(1): 91-95.

DOI：10.1536/ihj.15-271

• Right ventricular dysfunction
• Circulatory collapse
• Hypotension

Pulmonary embolism (PE) is a potentially life-threatening condition and the fact that 90% of PE originate from lower limb veins highlights the significance of early detection and treatment of deep vein thrombosis. (1)) Massive/high risk PE involving circulatory collapse or systemic arterial hypotension is associated with an early mortality rate of approximately 50%, in part from right ventricular (RV) failure.(2)) Intermediate risk/submassive PE, on the other hand, is defined as PE-related RV dysfunction, troponin and/or B-type natriuretic peptide elevation despite normal arterial pressure. (3)) Without prompt treatment, patients with intermediate risk PE may progress to the massive category with a potentially fatal outcome. In patients with PE and right ventricular dysRVD), in hospital mortality ranges from 5% to 17%, significantly higher than in patients without RVD. 4,5)

• 出版日期2016-1