Neonatal necrotising fasciitis - Varanasi experience

作者：Gangopadhyay Ajay Narayan; Pandey Anand^*; Upadhyay Vijay Dutt; Sharma Shiv Prasad; Gupta Dinesh Kumar; Kumar Vijayendra

来源：International Wound Journal, 2008, 5(1): 108-112.

DOI：10.1111/j.1742-481X.2007.00350.x

• Neonatal necrotising fasciitis
• Neonatal skin necrosis
• Survival

Neonatal necrotising fasciitis (NNF) is a rare and fatal disorder. Successful outcome depends on timely intervention. This paper presents single-centre experience of presentation, management and outcome of the condition. Fifteen patients of NNF were managed during the study period of 5 years. Parameters studied were age, sex, site of involvement and treatment. Treatment included intravenous (i.v.) antibiotics and conservative surgery. Age of presentation was 10-28 days. Male to female ratio was 2:1. Neck and scalp were the commonest site (53.3%). Culture reports were unimicrobial in 66% with predominance of Staphylococcus species. Predisposing factors included rural environment (100%), malnourishment (60%), boils (40%) and scratch injury (13%). Forty per cent had idiopathic NNF. Wound healing was by secondary intention in 46.6% and skin grafting in 53.3%. Overall survival was 80%, while the premature had poorer outcome. NNF is a serious disorder. Early treatment with i.v. antibiotics and supportive measures followed by debridement improves survival.

• 出版日期2008-3
• 单位河北医科大学