科研之友
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摘要
A short, formal synthesis of (+/-)-tylophorine was achieved using a radical-ionic sequence for the preparation of epoxides as the key step. This sequence, carried out between a phenantrenic allylic alcohol and iodoacetonitrile, provided an advanced intermediate containing most of the required elements for the final construction of the indolizidine scaffold.
- 出版日期2013-10-1
