Abnormalities of the penis in utero - hypospadias on fetal MRI

作者：Nemec Stefan F^*; Kasprian Gregor; Brugger Peter C; Bettelheim Dieter; Nemec Ursula; Krestan Christian R; Rotmensch Siegfried; Rimoin David L; Graham John M Jr; Prayer Daniela

来源：Journal of Perinatal Medicine, 2011, 39(4): 451-456.

DOI：10.1515/JPM.2011.042

• Associated pathologies
• fetal MRI
• hypospadias
• penile abnormalities

Objective: To demonstrate the visualization of penile abnormalities on fetal magnetic resonance imaging (MRI).
Methods: This retrospective study included five fetuses (25+0 to 31+6 gestational weeks) with penile abnormalities, positively depicted on fetal MRI, using prenatal ultrasonography (US) as a standard of reference. On MRI, the penis, as well as the scrotum and testicles, were evaluated. All fetal organs were reviewed to define penile abnormalities as isolated or in association with other anomalies. Furthermore, US and MRI findings were compared.
Results: Posterior hypospadias were demonstrated in all five fetuses, and abnormal testicular descent in two. Associated anomalies were present in all five fetuses on MRI, including abdominal/urogenital pathologies in four; brain pathologies in three; and craniofacial, cardiac, musculoskeletal, pathologies each in one fetus, and intrauterine growth retardation in one fetus. Compared to US, additional MRI findings were shown in four of five fetuses.
Conclusions: Our MRI results demonstrate the visualization of fetal penile abnormalities and associated pathologies, which may provide information for perinatal management. MRI may show additional findings compared to prenatal US in certain cases.

• 出版日期2011-7
• 单位河北医科大学