Adhesion of biocompatible and biodegradable micropatterned surfaces

作者：Kaiser Jessica S; Kamperman Marleen^*; de Souza Emerson J; Schick Bernhard; Arzt Eduard

来源：The International Journal of Artificial Organs, 2011, 34(2): 180-184.

DOI：10.5301/IJAO.2011.6393

• Bioinspiration
• Gecko adhesion
• Tissue engineering
• Biodegradability
• Tympanic membrane restoration

We studied the effects of pillar dimensions and stiffness of biocompatible and biodegradable micropatterned surfaces on adhesion on different compliant substrates. The micropatterned adhesives were based on biocompatible polydimethylsiloxane (PDMS) and biodegradable poly(lactic-co-glycolic) acid (PLGA) polymer systems. Micropatterned and non-patterned compliant PDMS did not show significant differences in adhesion on compliant mice ear skin or on gelatin-glycerin model substrates. However, adhesion measurements for micropatterned stiff PLGA on compliant gelatin-glycerin model substrates showed significant enhancement in pull-off strengths compared to non-patterned controls.

• 出版日期2011-2