A Randomized Trial to Increase Acceptance of Childhood Vaccines by Vaccine-Hesitant Parents: A Pilot Study

作者：Williams S Elizabeth^*; Rothman Russell L; Offit Paul A; Schaffner William; Sullivan Molly; Edwards Kathryn M

来源：Academic Pediatrics, 2013, 13(5): 475-480.

DOI：10.1016/j.acap.2013.03.011

• immunization
• parental attitude
• parental belief
• vaccine

OBJECTIVE: A cluster randomized trial was performed to evaluate an educational intervention to improve parental attitudes and vaccine uptake in vaccine-hesitant parents.
METHODS: Two primary care sites were randomized to provide families with either usual care or an intervention (video and written information) for vaccine-hesitant parents. Eligible parents included those presenting for their child's 2-week well-child visit with performance on the Parent Attitudes about Childhood Vaccines (PACV) survey suggesting vaccine hesitancy (score >= 25). Enrollees completed PACV surveys at the 2-month well-child visit and vaccination status at 12 weeks of age was assessed. The primary outcome was the difference in PACV scores obtained at enrollment and 2 months between the 2 groups. The proportion of on-time vaccination was also compared at 12 weeks.
RESULTS: A total of 454 parents were approached, and 369 (81.3%) participated; 132 had PACV scores of and were enrolled, 67 in the control group (mean PACV score 37) and 55 in the intervention group (mean PACV score 40). Twomonth PACV surveys were completed by 108 (similar to 90%) of enrollees. Parents in the intervention group had a significant decrease in PACV score at 2 months compared to control (median difference 6.7, P = .049); this remained significant after adjustment for baseline PACV score, race/ethnicity, and income (P = .044). There was no difference in the on-time receipt of vaccines between groups at 12 weeks.
CONCLUSIONS: A brief educational intervention for vaccine-hesitant parents was associated with a modest but significant increase in measured parental attitudes toward vaccines.

• 出版日期2013-10