Field trial on the simultaneous vaccination against porcine circovirus type 2 (PCV2) and Mycoplasma hyopneumoniae

作者：Herbich E^*; Heissenberger B; Ladinig A; Griessler A; Ritzmann M; Weissenbacher Lang C; Hennig Pauka I

来源：Tieraerztliche Praxis Ausgabe Grosstiere Nutztiere, 2013, 41(5): 279-288.

• Respiratory disease
• porcine respiratory disease complex (PRDC)
• postweaning multisystemic wasting syndrome (PMWS)
• field trial
• combined vaccine

Objective: The objective of the present study was to investigate whether a combined or concurrent application of two vaccines against Mycoplasma hyopneumoniae (M. hyo.) and porcine circovirus type 2 (PCV2) in suckling piglets can be as effective as the single use of both products. Material and methods: A total of 598 piglets were allocated to five groups. In the 1st and 3rd weeks of life the placebo Porcilis(R) Diluvac forte and the two vaccines Porcilis(R) M HYO (%26quot;M HYO%26quot;) and Porcilis(R) PCV (%26quot;PCV%26quot;) were administered according to the following scheme: group A: placebo/PCV; group B: M HYO/M HYO; group C: placebo/placebo; group D: M HYO/M HYO + PCV (combined single dose); group E: placebo/M HY + PCV (different injection sites). Lung lesions due to M. hyo. infection were recorded at slaughter, and average daily weight gain, morbidity, mortality, serum PCV2 load and specific humoral immune responses were compared between the groups. Local and systemic side effects were recorded. Results: Sporadic impairment of the herd health status due to piglet diarrhoea (n = 111) from the 1st to 3rd weeks of life were not associated with M. hyo. or PCV2. A tendency towards a higher average daily weight gain was found in vaccinated pigs compared to the control group. Slight differences between groups in terms of lung lesions, morbidity and mortality were not significant. M. hyo. and PCV2 antibody-titers were significantly higher in vaccinated than in non-vaccinated pigs. One pig from both group A (PCV2) and group C (placebo) displayed local reactions at the vaccination site. Conclusion and clinical relevance: A positive effect on animal health can be achieved by vaccination against M. hyo. and PCV2 in herds with suboptimal health status. A simultaneous vaccination either by a combined or concurrent application has no negative effect on health status. Simultaneous vaccination yielded the same positive effect on average daily weight gain as single vaccinations. Therefore, a simultaneous vaccination against M. hyo. and PCV2, which reduces workload and is beneficial for animal welfare, can be recommended.

• 出版日期2013