Aspirin underuse, non-compliance or cessation: Definition, extent, impact and potential solutions in the primary and secondary prevention of cardiovascular disease

作者：Biondi Zoccai Giuseppe^*; Wu Yangfeng; Serrano Carlos V Jr; Frati Giacomo; Agostoni Pierfrancesco; Abbate Antonio

来源：International Journal of Cardiology, 2015, 182: 148-154.

DOI：10.1016/j.ijcard.2014.12.091

• Aspirin
• Cardiovascular disease
• Cessation
• Compliance
• Discontinuation
• Underuse

Despite momentous breakthroughs in unraveling the pathophysiology of many chronic conditions and developing novel therapeutic agents, everyday clinical practice is still fraught with inadequate or inappropriate use of treatments with proven benefits. Aspirin is a paradigmatic example, as it is used for the primary and secondary prevention of cardiovascular disease and appears to have a beneficial impact on cancer risk. Yet, underuse, noncompliance or cessation of aspirin are not uncommon, may have an important clinical impact, and are not aggressively prevented or managed. Increasing the awareness of the extent and impact of aspirin underuse, noncompliance or cessation, and intensifying efforts at preventing them are worthy goals likely to yield significant benefits on cardiovascular morbidity and mortality worldwide, and possibly also on cancer outcomes.

• 出版日期2015-3-1
• 单位北京大学