A simple click generated probe for highly selective sequential recognition of Cu(II) and pyrophosphate

作者：Tang Lijun^*; Zhou Pei; Huang Zhenlong; Zhao Jia; Cai Mingjun

来源：Tetrahedron Letters, 2013, 54(45): 5948-5952.

DOI：10.1016/j.tetlet.2013.08.047

• Cu2+ recognition
• Pyrophosphate sensing
• Click chemistry

A click generated quinoline derivative (1) has been synthesized and used as a fluorescent probe for sequential recognition of Cu2+ and pyrophosphate (PPi) in DMSO/H2O (1:1, v/v, HEPES 20 mM, pH = 7.4) solution. Probe 1 displays high selectivity to Cu2+ ions, and the in-situ prepared probe 1-Cu2+ exhibits high selectivity toward pyrophosphate (PPi) with emission recovery of probe I. Therefore, 1-Cu2+ complex can be applied as a fluorescence turn-on probe for PPi with high selectivity and sensitivity.

• 出版日期2013-11-6
• 单位渤海大学