Acupuncture for Functional Dyspepsia: A Single Blinded, Randomized, Controlled Trial

作者：Jin, Yulian; Zhao, Qing; Zhou, Kehua; Jing, Xianghong; Yu, Xiaochun; Fang, Jiliang^*; Liu, Zhishun; Zhu, Bing

来源：Evidence-Based Complementary and Alternative Medicine, 2015, 2015: 904926.

DOI：10.1155/2015/904926

• GASTRIC MYOELECTRICAL ACTIVITY
• DIABETIC-PATIENTS
• ELECTROACUPUNCTURE
• SYMPTOMS
• STIMULATION
• TRANSLATION
• VALIDATION
• MANAGEMENT
• ANXIETY
• POINTS

In order to investigate the therapeutic potential of acupuncture on patients with functional dyspepsia (FD), patients were randomized to receive acupuncture at classic acupoints with manipulations (treatment group) versus acupuncture at nonacupoints without manipulation (control group) once every other day, three times a week, for one month and were followed up for three months. The primary outcomes included dyspeptic symptoms, quality of life, and mental status. The secondary outcomes included the fasting serum gastrin concentration, and frequency and propagation velocity of gastric slow waves. Sixty patients with FD were included, among whom, four dropped out. After one month's treatment, patients with FD showed significant improvements in primary (in both groups) and secondary (in the eight patients of the treatment group) outcomes as compared with baseline (P = 0.0078 to <0.0001); treatment group has better outcomes in all primary outcome measures (P < 0.0001 except for SDS (P = 0.0005)). Improvements on dyspeptic symptoms persist during follow-up (better in the treatment group). Acupuncture with manual manipulation had better effects on improving dyspeptic symptoms, mental status, and quality of life in patients with FD. These effects may be related to the increased frequency and propagation speed of gastric slow waves and serum gastrin secretion.

• 出版日期2015
• 单位中国中医科学院; 中国中医科学院广安门医院