Assessment of lower urinary tract symptoms in men by international prostate symptom score and core lower urinary tract symptom score

作者：Fujimura Tetsuya^*; Kume Haruki; Nishimatsu Hiroaki; Sugihara Toru; Nomiya Akira; Tsurumaki Yuzuri; Miyazaki Hideyo; Suzuki Motofumi; Fukuhara Hiroshi; Enomoto Yutaka; Homma Yukio

来源：BJU International, 2012, 109(10): 1512-1516.

DOI：10.1111/j.1464-410X.2011.10445.x

• LUTS
• assessment
• CLSS
• IPSS
• BPH

OBJECTIVE
International Prostate Symptom Score (IPSS) has been commonly used to assess lower urinary tract symptoms (LUTS). We have recently developed Core Lower Urinary Tract Symptom Score (CLSS). The aim of this study is to compare IPSS and CLSS for assessing LUTS in men.
PATIENTS AND METHODS
Consecutive 515 men fulfilled IPSS and CLSS questionnaires.
IPSS QOL Index was used as the QOL surrogate.
The clinical diagnoses were BPH (n = 116), BPH with OAB wet (n = 80), prostate cancer (n = 128), prostatitis (n = 68), underactive bladder (n = 8), others (n = 72), and controls (e.g., occult blood) (n = 42).
Simple statistics and predictability of poor QOL (QOL Index 4 or greater) were examined.
RESULTS
All symptom scores were significantly increased in symptomatic men compared with controls. Scores of corresponding symptoms of two questionnaires were significantly correlated (r = 0.58-0.85, all P < 0.0001).
A multivariate regression model to predict poor QOL indicated nine symptoms (daytime frequency, nocturia, urgency, urgency incontinence, slow stream, straining, incomplete emptying, bladder pain and urethral pain) as independent factors.
The hazard ratios for bladder pain (2.2) and urgency incontinence (2.0) were among the highest.
All the nine symptoms are addressed in CLSS, while three symptoms (urgency incontinence, bladder, and urethral pain) are dismissed in IPSS.
CONCLUSION
CLSS questionnaire is more comprehensive than IPSS questionnaire for symptom assessment of men with various diseases/conditions, although both questionnaires can capture LUTS with possible negative impact on QOL.

• 出版日期2012-5