A questionnaire-wide association study of personality and mortality: The Vietnam Experience Study

作者：Weiss Alexander^*; Gale Catharine R; Batty G David; Deary Ian J

来源：Journal of Psychosomatic Research, 2013, 74(6): 523-529.

DOI：10.1016/j.jpsychores.2013.02.010

• Minnesota Multiphasic Personality Inventory
• Mortality
• Negative Affect
• Personality
• Vietnam Experience Study
• Somatic Complaints

Objective: We examined the association between the Minnesota Multiphasic Personality Inventory (MMPI) and all-cause mortality in 4462 middle-aged Vietnam-era veterans. %26lt;br%26gt;Methods: We split the study population into half-samples. In each half, we used proportional hazards (Cox) regression to test the 550 MMPI items%26apos; associations with mortality over 15 years. In all participants, we subjected significant (p%26lt;.01) items in both halves to principal-components analysis (PCA). We used Cox regression to test whether these components predicted mortality when controlling for other predictors (demographics, cognitive ability, health behaviors, and mental/physical health). %26lt;br%26gt;Results: Eighty-nine items were associated with mortality in both half-samples. PCA revealed Neuroticism/ Negative Affectivity, Somatic Complaints, Psychotic/Paranoia, and Antisocial components, and a higherorder component, Personal Disturbance. Individually, Neuroticism/Negative Affectivity (HR = 1.55; 95% CI = 139, 1.72), Somatic Complaints (HR = 1.66; 95% CI = 1.52, 1.80), Psychotic/Paranoid (HR = 1.44; 95% CI = 1.32, 1.57), Antisocial (HR = 1.79; 95% CI = 1.59, 2.01), and Personal Disturbance (HR = 1.74; 95% CI = 1.58, 1.91) were associated with risk. Including covariates attenuated these associations (28.4 to 54.5%), though they were still significant. After entering Personal Disturbance into models with each component, Neuroticism/Negative Affectivity and Somatic Complaints were significant, although Neuroticism/ Negative Affectivity%26apos;s were now protective (HR = 0.73; 95% CI = 0.58, 0.92). When the four components were entered together with or without covariates, Somatic Complaints and Antisocial were significant risk factors. %26lt;br%26gt;Conclusions: Somatic Complaints and Personal Disturbance are associated with increased mortality risk. Other components%26apos; effects varied as a function of variables in the model.

• 出版日期2013-6