Secondary metabolites from the aerial parts of Centaurea pannonica (Heuff.) Simonk. from Serbia and their chemotaxonomic importance

作者：Ifantis Tanja Milosevic; Solujic Slavica; Pavlovic Muratspahic Dragana; Skaltsa Helen^*

来源：Phytochemistry, 2013, 94: 159-170.

DOI：10.1016/j.phytochem.2013.05.014

• C. pannonica (Heuff.) Simonk.
• Centaurea L.
• Centaurea jacea group
• NMR
• Guaianolides
• Flavonoids
• Lignans
• Chemotaxonomy

The non polar extract of Centaurea pannonica (Heuff.) Simonk., growing wild in Serbia, was studied and twenty-five compounds including 14 sesquiterpene lactones, 7 flavonoids, 3 lignans and 1 phenylpropanoid glycoside were isolated. All compounds were isolated for the first time from this species. Among them, one germacranolide 2 alpha-hydroxy, 8-dehydroxy 15-O-methacrylate salonitenolide (1) and two guaianolides 2 alpha,8 alpha-dihydroxy-dehydrocostus lactone (2) and pannonin (3) are new natural compounds. The structures of the compounds were established on the basis of spectroscopic analyses (UV, IR, HREIMS and 1D %26 2D NMR). The chemical profile of C. pannonica, which belongs to the %26quot;Centaurea jacea%26quot; group, was compared to previously studied taxa of the same group and used to assess the phylogenetic relationships in the group.

• 出版日期2013-10