科研之友
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摘要
This study discloses a general and convergent route for the regio- and stereospecific construction of the CS glycosyl angucycline framework of mayamycin. C-Glycosidation, dearomatization, and Hauser annulation are the key steps. The synthetic analogues show cytotoxicity against different human cancer cell lines with IC50 values between 16.4 and 1.2 mu M.
- 出版日期2013-10-4
