Antimicrobial Effect of alpha- or beta-Cyclodextrin Complexes with Trans-Cinnamaldehyde Against Staphylococcus aureus and Escherichia coli

作者：Chun Ji Yeon; Jo Yeon Ji; Bjrapha Piyawan; Choi Mi Jung; Min Sang Gi^*

来源：Drying Technology, 2015, 33(3): 377-383.

DOI：10.1080/07373937.2014.957388

• Antibacterial activity
• Cyclodextrin
• Escherichia coli
• Inclusion method
• Staphylococcus aureus
• trans-cinnamaldehyde

Molecular inclusion or encapsulation based on cyclodextrin (CD) is the most widely used method in encapsulation technology. - and -CD complexes consisting of antibacterial trans-cinnamaldehyde were prepared by the molecular inclusion method. The characteristics of the complex were determined, including examination of their antimicrobial effects after the drying process. The particle sizes of the trans-cinnamaldehyde-CD complexes were observed in the range of 300 to 500nm after production. Particle sizes of both trans-cinnamaldehyde-CD complexes were slightly increased increasing in a dose-dependent manner of trans-cinnamaldehyde. Although -CD complexes were larger than -CD complexes, they possessed a lower polydispersity index with a narrow size distribution. The encapsulation efficiency of trans-cinnamaldehyde-CD complexes was >90% in all formulations. Trans-cinnamaldehyde affected reduction of Staphylococcus aureus and Escherichia coli, with antibacterial activity increasing in a dose-dependent manner of trans-cinnamaldehyde concentration. In addition, -CD complexes showed more effective antimicrobial effects compared to -CD complexes.

• 出版日期2015