科研之友
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摘要
Immunisation of Houghton White Leghorn line 15I and 6(1) chickens with empty reticuloendotheliosis virus particles elicited a primary antibody response which is probably directed against the viral envelope glycoproteins gp73/71 and gp22. Antibodies in line 15I birds were shown to be non-neutralising and did not protect against the tumourigenic effects of reticuloendotheliosis virus, strain T. However, immunised line 6(1) chicks did not exhibit the runting syndrome associated with reticuloendotheliosis virus infection, suggesting that antibody against viral coat proteins may play a role in modulating pathogenesis in certain lines of chicken.
- 出版日期1993-9
